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Purification of Protein by HIC

Mechanistic Modeling for Improving Process Optimization
In collaboration with GSK, this article outlines how a simple chromatographic model can predict the impact of pH and ionic strength on HIC chromatograms.   Hydrophobic interaction chromatography (HIC) is a separation technique widely used for...
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Purification of protein by Hydrophobic Interaction Chromatography (HIC): mechanistic modeling for improved understanding and process optimization

Presented by Yohann Le Guennec
Hydrophobic Interaction Chromatography (HIC) is a chromatographic separation technique that is today successfully used for the purification of proteins. However, to achieve highly efficient separations, key operating parameters – like pH and ionic...
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