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Case studies & Application Notes

Application Note: Design of a multicolumn process for mAb capture

Mechanistic simulation to assess the impact of the number of columns on key performance indicators
There is an increasing interest in using multicolumn processes for the capture of monoclonal antibobies (mAbs) by affinity chromatography . However, selecting and designing the most suitable process is not straightforward. There are indeed a wide...
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Designing affinity chromatographic processes for the capture of antibodies

Part I: A simplified approach
ABSTRACT Protein A affinity chromatography is a standard technique for the purification of therapeutic antibodies. Recently, multi-column chromatographic processes have emerged to turn classical capture processes into more efficient and continuous...
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