We help develop, evaluate, and optimize (bio)chemical processes

Our proven methodology combines our/your expertise, well-targeted experiments, and predictive simulation to solve the biggest challenges in (bio)process development.

Your Process Secured and Optimized… It’s a Fact!

Our combined offering

Proxima Software Suite

Proxima Ionic
Design chromatographic processes
Proxima Basic design
Drawprocess diagrams and establish mass/heat balances
Proxima eval
Perform economic and environmental evaluation
Proxima Multistep
Describe your multistep synthesis within a chemist-friendly interface

Consulting

  • Improve process performances such as yield, productivity, sustainability
  • Optimize experimental plans
  • Improve process understanding
  • Develop mechanistic models
  • Perform simulations as a service
  • Determine the design space
  • Troubleshoot existing processes

A Result oriented partner

Polypeptide Group

Reduced solvent consumption by 57% in peptide solid phase synthesis. Read more

Aker Biomarine

Doubled productivity of a multi-column ion exchange chromatographic process with increased purity. Read more

Fareva

Re-established an antibiotic purification process that failed delivering the target purity following a change in raw material. Read more

GSK

Reduced experimental work by 4 compared to DoE for an oligonucleotide ion exchange process, while getting much more knowledge. Read more


They trust us

They speak about us


Recent News

Ypso-Facto are pleased to announce that they got granted three families of patents

  • March 27, 2024
Ypso-Facto are pleased to announce that they got granted three families of patents in the last months: Method and device for...

Ypso-Facto cooperates with SmarSEP Industries to provide process modeling and numerical simulation services for the Chinese Industrial Biotechnology Market.

  • February 26, 2024
Ypso-Facto® (Nancy, France), a leading provider of (bio)chemical process simulation software and services, has announced a cooperation...

Events

2nd Oligonucleotide Manufacturing Symposium event

  • March 19, 2024
Ypso-Facto is excited to announce its participation in the 2nd Oligonucleotide Manufacturing Symposium , taking place on April 23, 2024, in Glasgow.  This symposium will bring together key stakeholders...

BioProcess International Europe

  • March 18, 2024
We are pleased to announce our participation in BioProcess International Europe , scheduled for April 9-12 in Vienna. This key event in biotechnology focuses on advancements in bioproduction, including...

Latest publications

Bioprocess Simulation: Why the Industry Needs To Embrace Engineering Rather Than Empirical Approaches?

  • March 07, 2024
  • by Ypso-Facto
In 1903, the Wright brothers built the first functioning airplane, and botanist Mikhail Tsvet became the first scientist to use chromatography to separate components of a solution (carotene pigments, in his case). Now, 120 years later, new airplanes can be simulated with great precision and confidence — but chromatography process development in the biopharmaceutical industry still relies heavily on trial and error. So why are we so far behind in using simulation to guide such work? Click here to read the article in the e-book: Biomanufacturing... Read more

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

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