"Solid-Phase Peptide Synthesis (SPPS) is well established and routinely applied on efficient automatic synthesisers, which are available at laboratory scale. However, manufacturing peptides at industrial scale remains a major challenge, considering the complexity of these multi-step syntheses, the long lead times and the large volume of reagents and solvents required to produce the final API. In 2013, we published an article looking at the way to overcome these challenges from a holistic point of view. This article presents the latest practices contributing... Read more
Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.