Improving an industrial fermentation

Challenge

  • Scale-up of a industrial fermentation process

  • Need to improve productivity and process stability

Methods

  • Establishment of mass balances, calculations of yields and Oxygen Uptake Rates

  • Identification of key process parameters

  • On site support during production campaign

Achievements

  • Definition of a new protocol at pilot scale

  • Real time corrective actions to address process deviations

  • Improvement of process performances 

Contact us to discuss your own challenges! 

Ypso-Facto has been helping Pharmaceutical and Biopharmaceutical companies optimize their processes since 2014. We offer technology enabled services and proprietary software to solve some of our industries biggest challenges : make (bio)pharmaceutical processes safer, more cost efficient, and environmentally friendly.

We have a unique approach based on technologies which can combine multiple dimensions:

  • The educated guess or expertise of the experts, which we call G
  • The use and contextualization of experimental data, which we call X
  • And the predictive simulation based on mechanistic modelling, which we call P.

Depending on your product and process, we have mechanistic models that we can use, or we can work with your experimental data to build one. Altogether, that is our unique GPX approach.

#biotech #fermentation #scaleup #productivity #stability #pilotscale #software #mechanistic #modeling #simulation

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