- September 12, 2023
Reduced solvent consumption by 57% in peptide solid phase synthesis
"During our cooperation with Ypso-Facto, by associating our respective expertises, predictive simulation and experiments, we managed reducing by 57 % the solvent use for resin washing during SPPS." Olivier LUDEMANN-HOMBOURGER, Director Global - Innovation & Technology, PolyPeptide...
- June 12, 2023
Comparison of single and multi-column processes with mechanistic simulation
Multicolumn Chromatography is a strong possible alternative to single-column chromatography for improving process performances. Mechanistic simulations can be used to investigate several process options and quantify the impact on key performance indicators, thus providing a platform to make...
- May 08, 2023
Modeling: Mechanistic or Statistical ? Part 2 : Making a choice
Interested by knowing the differences between statistical and mechanistic approach? Click here to access part 1 of the article "Modeling : Mechanistic vs Statistical ? Part 1 : Modeling expectations" All modeling approaches need to be fed with experimental data to identify parameters. A...
- March 13, 2023
Modeling: Mechanistic or Statistical ? Part 1 : Modeling expectations
Digital tools are used for well-known applications in our everyday life: energy production, navigation, drugs development, weather prediction, diseases detection. They are useful because they allow predicting: weather, illness, position and direction, conditions for minimizing energy...
- February 02, 2023
How to easily extract relevant information and KPIs from your experimental data ?
Your data is one of your most valuable resources. But without a tool to exploit them in a structured way, you miss information that allow you to improve efficiency, increase productivity or decrease the experimental work burden. This is why we have developed Ypso-Ionic®, which allows to...
- January 12, 2023
Ensure reliable tech transfer thanks to comprehensive and structured data
Ypso-ionic® is a software solution for designing chromatographic processes. Compared to a classical ELN, Ypso-Ionic allows to describe, store and share your experimental data in a standardized, contextualized and rational manner across all users. Ypso-Ionic’s proprietary Y|F Data format...
- November 21, 2022
Maximize the value of your experimental data... what does it mean ?
Ypso-Ionic is a collaborative software for designing chromatographic process, but not only! It is an innovative solution for data management and reliable tech transfer. Hence, you can : easily compare different batches to check consistency of your process explicitly describe your recipes...
- October 12, 2022
Feedback from Bioproduction conference
End of September, we attended the 7th edition of conference Bioproduction organized by MabDesign, in Lyon. The focus this year was on the development and bioproduction of therapeutics drugs such as mAbs. There were several presentations both from SME and large biopharma groups and a section in the...
- September 14, 2022
Boosting a process with digital tools: Purification of oligonucleotides by ion exchange
Purification of oligonucleotides by ion exchange (IEX) is complex and many operating parameters need to be selected. There is a high interest in developing digital tools allowing to speed up process development, securing scale-up and decreasing waste. We present an innovative mechanistic model for...
Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.