- November 02, 2020
NEW ARTICLE – Fareva and Ypso-Facto investigate the purification of an antibiotic by ion-exchange
This article is based on a real industrial purification process by Fareva and highlights the power of mechanistic modeling for process development: Our client needed to change a raw material to secure his supply chain. From a process point of view, it was supposed to be seamless. However, a simple...
- May 13, 2020
Indépendance sanitaire : La tribune de Roger-Marc Nicoud (French)
La crise actuelle rappelle à l’Europe (et sans doute à l’Amérique du Nord) les limites de la délocalisation de la production. C’est le cas pour de nombreux produits, incluant bon nombre d’ingrédients pharmaceutiques actifs (API) et de médicaments en général. Cela ouvre la...
- May 12, 2020
Feature article – Regaining independence in API production: A chance for European CDMOs
The current crisis has highlighted the dependence of European and, indeed, North American countries on delocalised production. This is the case for many goods, including APIs and drugs in general. The opportunity is now there for European CDMOs to win additional business, but effort and adaptation...
- February 01, 2020
Ypso-Facto, Your Process Secured and Optimized... it’s a Fact
ABOUT YPSO-FACTO Ypso-Facto is a company helping industrial firms to develop, optimize and secure their chemical and bio-processes. We commit to keeping our interests aligned with the ones of our customers. For this reason, we remain deliberately free from industrial property rights, production...
- September 16, 2019
Digitalization for CDMOs: thinking outside the silos!
Marc-Olivier Simon and Moïse Bitton discuss the needs of CDMOs in terms of digitalization of their activities and the tools available on the market (ELN, LIMS, LES, SDMS, KM, QMS, MES etc.). While (Big) Pharmas have embraced digitalization, CDMOs seem far behind. The author see this as the result...
- December 06, 2018
Modern Simulation Tools: Expanding Applications
New user-friendly solutions help chemical processors tackle tasks beyond design and optimization Initially, steady-state simulation was used in the chemical process industries (CPI) to design a plant or a process. Advances in the technology, along with the need to produce more product in a more...
- November 26, 2018
A new era in life sciences software
Life sciences industries still use outdated tools and methodologies to develop, optimise and operate their (bio)molecule production processes. Ypso-Facto proposes to take a fresh look at the needs and expectations of this sector. Read the full article in the last edition of Speciality Chemicals...
- June 13, 2018
Panel discussion on flow chemistry
"By adopting chemical engineering good practices earlier in process development, a major step forward would be taken" Read the full panel discussion in Chemistry Today, vol. 36 (3), 2018, pp 26-34
- October 06, 2017
Streamlining process development with simulation software tools
Nowadays process development is generally experiment-based with a traditional trial-and-error approach, direct scale-up and simple use of statistical tools. We are convinced that the fine chemical and biochemical industries will evolve towards more digitally designed processes based on...
Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.