Follow us:

Publications

  • Home
  • Publications
  • A continuum theory for multicomponent chromatography modeling

A continuum theory for multicomponent chromatography modeling

David Pfister, Massimo Morbidelli,* Roger-Marc Nicoud

  • by Ypso-Facto
  • March 22, 2016
A continuum theory for multicomponent chromatography modeling

ABSTRACT:

A continuum theory is proposed for modeling multicomponent chromatographic systems under linear conditions. The model is based on the description of complex mixtures, possibly involving tens or hundreds of solutes, by a continuum. The present approach is shown to be very efficient when dealing with a large number of similar components presenting close elution behaviors and whose individual analytical characterization is impossible. Moreover, approximating complex mixtures by continuous distributions of solutes reduces the required number of model parameters to the few ones specific to the characterization of the selected continuous distributions. Therefore, in the frame of the continuum theory, the simulation of large multicomponent systems gets simplified and the computational effectiveness of the chromatographic model is thus dramatically improved.

REFERENCE

 
Publication Date (Web): March 22, 2016
Copyright © 2016 Elsevier B.V.

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

Learn more

Contact Us
© Ypso-Facto 2014 - Powered by Ealys | Legal Information