We help develop, evaluate, and optimize (bio)chemical processes

Our proven methodology combines our/your expertise, well-targeted experiments, and predictive simulation to solve the biggest challenges in (bio)process development.

Your Process Secured and Optimized… It’s a Fact!

Our combined offering

Proxima Software Suite

Proxima Ionic
Design chromatographic processes
Proxima Basic design
Drawprocess diagrams and establish mass/heat balances
Proxima eval
Perform economic and environmental evaluation
Proxima Multistep
Describe your multistep synthesis within a chemist-friendly interface

Consulting

  • Improve process performances such as yield, productivity, sustainability
  • Optimize experimental plans
  • Improve process understanding
  • Develop mechanistic models
  • Perform simulations as a service
  • Determine the design space
  • Troubleshoot existing processes

A Result oriented partner

Polypeptide Group

Reduced solvent consumption by 57% in peptide solid phase synthesis. Read more

Aker Biomarine

Doubled productivity of a multi-column ion exchange chromatographic process with increased purity. Read more

Fareva

Re-established an antibiotic purification process that failed delivering the target purity following a change in raw material. Read more

GSK

Reduced experimental work by 4 compared to DoE for an oligonucleotide ion exchange process, while getting much more knowledge. Read more


They trust us

They speak about us


Recent News

New leadership, shared ambition

  • March 06, 2025
Nearly six years ago, we joined the Ypso-Facto journey, eager to contribute and learn from a company driven by science and...

Time flies like an arrow…

  • February 18, 2025
40 years have gone by since I graduated, 30 years since I created Novasep and 10 years since I created Ypso-Facto. At...

Events

SECF Sustainable pharmaceutical Industry

  • July 02, 2025
Ypso-Facto is pleased to take part in the SECF Sustainable Event 2025 in Nancy. Lucrèce Nicoud, co-CEO at Ypso-Facto, will be speaking during Session 3: Process Improvement & Intensification,...

National Biomedicines Manufacturing Day

  • June 05, 2025
Launched by France BioLead, the National Biomedicine Manufacturing Day (JNBB) is a yearly event that brings together industry leaders, researchers, students, and the public to showcase the future of...

Latest publications

mAb production kinetics in CHO batch culture: exploring extracellular and intracellular dynamics

  • August 13, 2025
  • by Ypso-Facto
We are pleased to announce that Alejandro Avilan Garzon, PhD, doctoral researcher conducting his PhD work at Ypso-Facto, has recently published part of his research in Frontiers in Bioengineering and Biotechnology, in collaboration with our colleague David Pfister. The study investigates key aspects of monoclonal antibody (mAb) production in CHO batch cultures, combining extracellular and intracellular data to gain a deeper understanding of process dynamics. This work contributes to our ambition to apply Ypso-Facto’s proven DSP methodology to the... Read more

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

Learn more

Contact Us
  • Address: 19 avenue Foch
    54000 NANCY - FRANCE
  • LU +352 20 21 39 14
    FR +33(0) 355 961 650
  • contact@ypso-facto.com
© Ypso-Facto 2014 - Powered by Ealys | Legal Information