We help develop, evaluate, and optimize (bio)chemical processes

Our proven methodology combines our/your expertise, well-targeted experiments, and predictive simulation to solve the biggest challenges in (bio)process development.

Your Process Secured and Optimized… It’s a Fact!

Our combined offering

Proxima Software Suite

Proxima Ionic
Design chromatographic processes
Proxima Basic design
Drawprocess diagrams and establish mass/heat balances
Proxima eval
Perform economic and environmental evaluation
Proxima Multistep
Describe your multistep synthesis within a chemist-friendly interface

Consulting

  • Improve process performances such as yield, productivity, sustainability
  • Optimize experimental plans
  • Improve process understanding
  • Develop mechanistic models
  • Perform simulations as a service
  • Determine the design space
  • Troubleshoot existing processes

A Result oriented partner

Polypeptide Group

Reduced solvent consumption by 57% in peptide solid phase synthesis. Read more

Aker Biomarine

Doubled productivity of a multi-column ion exchange chromatographic process with increased purity. Read more

Fareva

Re-established an antibiotic purification process that failed delivering the target purity following a change in raw material. Read more

GSK

Reduced experimental work by 4 compared to DoE for an oligonucleotide ion exchange process, while getting much more knowledge. Read more


They trust us

They speak about us


Recent News

Bioprocess Development Symposium Celebrating Ypso-Facto’s 10th Anniversary

  • October 08, 2024
On October 2-3 2024, Ypso-Facto marked a significant milestone by hosting the Bioprocess Development Symposium in celebration of...

Ypso-Facto are pleased to announce that they got granted three families of patents

  • March 27, 2024
Ypso-Facto are pleased to announce that they got granted three families of patents in the last months: Method and device for...

Events

TIDES Europe : Oligonucleotide and Peptide Therapeutics

  • October 02, 2024
Ypso-Facto will exhibit at  TIDES Europe , the industry's leading event in Europe to accelerate therapeutics to market by expediting R&D, improving CMC efficiency and building new partnerships.  ...

SPICA 2024 : 19th International Symposium on Preparative and Industrial Chromatography and Allied Techniques

  • September 10, 2024
Ypso-Facto is thrilled to be part of SPICA 2024, an international event celebrating the latest innovations and best practices in Preparative and Industrial Chromatography.  The conference...

Latest publications

Oligonucleotide Purification by Ion Exchange Chromatography : Step-by-Step Guide to Process Understanding, Modeling, and Simulation

  • April 12, 2024
  • by Ypso-Facto
  Check out  Ypso-Facto's new publication  on oligonuclotide purification by Ion Exchange Chromatography in collaboration with GSK , Astrazeneca and Johnson & Johnson . ABSTRACT Oligonucleotides have emerged as a promising class of pharmaceuticals, leading to significantly increased demand. Oligonucleotides are typically produced by solid-phase synthesis and then purified by ion exchange or reverse-phase chromatography. Predictive simulation is a valuable tool to help  reduce process development times, secure scale-up, and decrease... Read more

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

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