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TIDES Europe : Oligonucleotide and Peptide Therapeutics

30 Oct - 1 Nov 2023 in Amsterdam (Booth 13)

  • by Ypso-Facto
  • October 03, 2023
TIDES Europe : Oligonucleotide and Peptide Therapeutics

Ypso-Facto will exhibit at TIDES Europe, the industry's leading event in Europe to accelerate therapeutics to market by expediting R&D, improving CMC efficiency and building new partnerships. 

Access new data & case studies from world-renowned speakers and companies across the entire landscape of oligonucleotides, peptides, mRNA, drug delivery and partnering strategies -- from discovery to market, with an emphasis on the European region.

Save the date : 30 Oct - 1 Nov 2023 in Amsterdam (booth 13)

Poster : Comparison of single and multi-column processes with mechanistic simulation: Application to oligonucleotide purification by ion exchange

Multicolumn Chromatography is a strong possible alternative to single-column chromatography for improving process performances. Mechanistic simulations can be used to investigate several process options and quantify the impact on key performance indicators, thus providing a platform to make informed decisions prior to investing.

In this poster, we show an illustration of a rational comparison between the single-column process and the MCSGP process performed with the software Ypso-Ionic® applied to the example of oligonucleotide purification by ion exchange chromatography.

Take Home Message : Mechanistic simulation is a powerful tool capable of assessing several process options.

The most suitable process for a given purification strongly depends on the objectives, constraints and levers of actions.  

We would be delighted to meet with you and discuss your needs around peptides or oligonucleotides synthesis and purification. Should you be interested in improving target performances (yield, purity, productivity), minimizing your environmental impact or digital transformation, we have the expertise and relevant digital solutions to support your manufacturing strategy. Book a meeting to learn more about our consulting services and software solutions : 

Interested attendees may have a look at our last webinar: 

Getting your process up to speed with digital tools; purification of oligonucleotides by ion exchange chromatography

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

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