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We develop, secure and optimize your chemical and bio processes
  • Continuous bio-processing
    Workshop by R.-M. Nicoud and M. Holzer at BioProduction in Dublin, 16th Oct 2017
  • Join us
    Come and hear about "batch vs. continuous chemical production processes", lecture by Dr Kobl at OPRD in Stockholm, 27-29th Sept
    We investigate industrial processes with (bio)chemist eyes through process engineer glasses
    We assist you from the concept to the production via robust and innovative processes
  • Ypso Facto
    We combine industrial experience with scientific expertise to provide solutions at the cutting edge of science and technology

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We create pioneering scientific solutions, complying with the most demanding technical and industrial constraints


of International


process evaluations


of activity
linked to chemistry


of revenues
dedicated to research

Our skills

  • Process Evaluation
  • Modeling specific unit operations
  • Understanding of production and application of molecules
  • Knowledge of industrial environment

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2 min to discover Ypso-Facto

Recent News

BioProduction Congress

  • September 20, 2017
Join us at the Mammalian and Microbial Biopharmaceutical Manufacturing congress. Ypso-Facto delivers a Workshop on "Continuous...

9th Symposium on Continuous Flow Reactor Technology for Industrial Applications

  • September 20, 2017
R.-M. Nicoud delivers a lecture on "Adapting process engineering to (bio)chemists for the development of smarter processes". ...

Last Publication

Designing affinity chromatographic processes for the capture of antibodies

ABSTRACT Protein A affinity chromatography is a standard technique for the purification of therapeutic antibodies. Recently, multi-column chromatographic processes have emerged to turn classical capture processes into more efficient and continuous systems. The design of such chromatographic processes, be they single-column or multi-column systems, is described in this work. A rational method to conceive, scale-up and compare processes is proposed and illustrated with different examples. All along this article, the results of the equilibrium theory... Read more

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

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