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We develop, secure and optimize your chemical and bio processes
    Advanced SPPS - Discussion on large scale peptide synthesis on solid supports by PolyPeptide Laboratories and Ypso-Facto
    We investigate industrial processes with (bio)chemist eyes through process engineer glasses
    We assist you from the concept to the production via robust and innovative processes
  • Ypso Facto
    We combine industrial experience with scientific expertise to provide solutions at the cutting edge of science and technology

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We create pioneering scientific solutions, complying with the most demanding technical and industrial constraints


of International


process evaluations


of activity
linked to chemistry


of revenues
dedicated to research

Our skills

  • Process Evaluation
  • Modeling specific unit operations
  • Understanding of production and application of molecules
  • Knowledge of industrial environment

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2 min to discover Ypso-Facto

video : discover Ypso-Facto

Recent News

BioProcess International Europe

  • March 29, 2019
Ypso-Facto will be at BPI Europe in Vienna.   Come and hear the lecture by H. Osuna on 2nd April 2019:   Modeling and...

2nd Bioprocessing Summit Europe

  • March 18, 2019
Ypso-Facto will be at the 2nd Bioprocessing Summit Europe, with a lecture by R.-M. Nicoud on "Modeling and Simulation of Ion-Exchange...

Last Publication

Advanced SPPS

"Solid-Phase Peptide Synthesis (SPPS) is well established and routinely applied on efficient automatic synthesisers, which are available at laboratory scale. However, manufacturing peptides at industrial scale remains a major challenge, considering the complexity of these multi-step syntheses, the long lead times and the large volume of reagents and solvents required to produce the final API. In 2013, we published an article looking at the way to overcome these challenges from a holistic point of view.  This article presents the latest practices contributing... Read more

Ypso-Facto is a service company helping industrial firms to develop, optimize and secure their chemical processes and bioprocesses.

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